Pufferfish Poisoning (2024)

Pufferfish Poisoning Overview

The poison found in pufferfish, blowfish, balloon fish, toads, sunfish, porcupine fish, toadfish, globefish, and swellfish is a tetrodotoxin. This is one of the most toxic poisons found in nature. Most people who eat pufferfish do so intentionally; pufferfish are considered an Asian delicacy, served in some types of sushi and sashimi. Unless the chef is specially trained to cut the meat in a particular fashion, the dish may contain a large amount of the toxin. Pufferfish poisoning is similar to paralytic shellfish poisoning.

Pufferfish Poisoning Symptoms

  • Symptoms generally occur 10-45 minutes after eating the pufferfish poison and begin with numbness and tingling around the mouth, salivation, nausea, and vomiting.
  • Symptoms may progress to paralysis, loss of consciousness, and respiratory failure and can lead to death.

Pufferfish Poisoning Treatment

  • Vomiting should be induced if the poisoned person is awake and alert and has eaten the fish within 3 hours.
  • The person may become paralyzed. Artificial respirations may keep the person alive until medical attention in a hospital's emergency department is possible.
  • Rapidly turn the person onto their side if vomiting occurs.

When to Seek Medical Care

Seek medical treatment as soon as possible.

Synonyms and Keywords

wilderness: pufferfish poisoning, puffer fish poison, puffer fish toxin, pufferfish toxin, tetrodotoxin, poison, poisoning, blue-ringed octopus bite, food poisoning, fish poisoning

Pufferfish Poisoning (2024)

FAQs

Is it possible to survive pufferfish poisoning? ›

The short answer is no. Humans can not survive being poisoned by pufferfish. There is also no known antidote. The rare instances where people are allowed to prepare and eat puffer fish still carry hefty possibilities of death with them.

Why is there no antidote for puffer fish? ›

Because the toxin is heat-stable, cooking does not destroy it. The toxin works by blocking sodium channels, in turn causing gastrointestinal, neurologic, and cardiac symptoms in patients with tetrodotoxin toxicity. There is currently no known antidote.

What is the response of a puffer fish? ›

The inflation response of pufferfishes is one of the most iconic predator defence strategies in nature. Current dogma suggests that pufferfish inflation represents a breath-holding response, whereby gill oxygen uptake ceases for the duration of inflation and cutaneous respiration increases to compensate.

Is puffer fish poison detectable? ›

Cases of TTX poisoning most often result from puffer fish ingestion. Diagnosis is mainly from patient's signs and symptoms or the detection of TTX in the leftover food. If leftover food is unavailable, the determination of TTX in the patient's urine and/or plasma is essential to confirm the diagnosis.

How long does fugu poison take? ›

Death may occur as early as 20 minutes, or as late as 24 hours, after exposure; but it usually occurs within the first 4 to 8 hours. Patient/victims who live through the acute intoxication in the first 24 hours usually recover without residual deficits.

How did Homer survive fugu? ›

But the reality of fugu is encapsulated by that same episode's surprise ending. Homer survives: he hasn't eaten the poisonous part of the fish after all. Very few people, as it turns out, get sick after eating blowfish in Japan, and fewer still die.

What is the most poisonous fish to eat? ›

The torafugu, or tiger pufferfish (Takifugu rubripes), is the most prestigious edible species and the most poisonous.

Are sharks immune to pufferfish poison? ›

To humans, tetrodotoxin is deadly, up to 1,200 times more poisonous than cyanide. There is enough toxin in one puffer fish to kill 30 adult humans, and there is no known antidote. Sharks are the only species immune to the puffer fish's toxin. They can eat puffer fish without any negative consequences.

Is fugu legal in the US? ›

If you consume it, you may experience paralysis and asphyxiation. Fugu is not technically illegal to consume in the U.S.. Some chefs can undergo the intense training and certification process required to prepare the fish. But those chefs are few and far between. That makes fugu de facto banned.

Do pufferfish puff up when scared? ›

Pufferfish will “puff up” as a defense mechanism if they are threatened. A shape that is more than double its original size, round and sometimes covered in spines is much more difficult to bite and isn't very appetizing to a predator.

What happens when a pufferfish blows up? ›

When a puffer fish puffs up, it takes in water to increase its size. This violently forces the puffer's organs to be pressed to the side, inside the body causing the organs to flatten. This creates an extreme amount of stress for the pufferfish. In some cases, the pufferfish dies from this stress.

What happens if a puffer fish inhales air? ›

If the fish is inflated on the surface, it is likely to ingest air. The air can be difficult to expel and can cause the death of the fish, since the fish floats and can not leave the surface.

How long does it take for puffer fish poison to kick in? ›

Pufferfish poisoning proceeds extremely rapidly, with death occurring around four to six hours after eating pufferfish. Between 20 minutes and 3 hours after eating, numbness begins to occur in the lips, the tip of the tongue, and the fingertips.

What is the mortality rate of tetrodotoxin? ›

The mortality rate was 13.5%. The violent neurotoxin is present in puffer fish and occurs in other marine animals. Without adequate therapy, patients may have serious morbidity or even succumb.

How can humans avoid tetrodotoxin? ›

This toxicosis may be avoided by not consuming animal species known to contain tetrodotoxin, principally pufferfish; other tetrodotoxic species are not usually consumed by humans. Poisoning from tetrodotoxin is of particular public health concern in Japan, where "fugu" is a traditional delicacy.

Is there an antidote for fugu? ›

Blowfish, known in Japan as fugu, is a highly prized delicacy both as sashimi or as an ingredient in soup, but the fish's liver, ovaries and skin contain the poison tetrodotoxin and the parts must be removed by specially trained and licensed preparers. There is no known antidote to the poison.

Has anyone survived eating fugu? ›

More than 60% of all fugu poisonings will end in death. After the toxin has been consumed, you have less than sixty minutes to get respiratory treatment which is your only hope in surviving the effects of this powerful poison.

Is fugu poisoning painful? ›

Fugu-poisoned people first begin to feel numbness around their mouths. Paralysis follows, and then a painful death by asphyxiation. There is no known antidote. Because of the delicacy's potential to kill customers, chefs must train for at least three years before they can even take the fugu certification test.

How many fugu related deaths? ›

Despite the danger and risks, fugu has grown in popularity especially among gourmets and thrill seekers and is now also eaten countries outside Japan – at times, unregulated. In 2020, food poisoning killed three people in the Philippines after they ate pufferfish from a local barbecue stand.

How many people have died from fugu poisoning? ›

Twenty-three people have died in Japan after eating fugu since 2000, according to government figures. Most of the victims are anglers who rashly try to prepare their catch at home.

How fat did Homer get? ›

With Bart and Dr Nick's help, Homer eventually increases his weight to 315 pounds (143 kg) and Mr. Burns installs a stay-at-home work terminal in the Simpson house.

What fish has killed the most humans? ›

Of the estimated 1,200 venomous fish species on Earth, the stonefish is the most lethal – with enough toxin to kill an adult human in under an hour.

What is the most toxic fruit? ›

The manchineel tree is the most dangerous tree on the planet. A single bite of the fruit can lead to death, and touching the bark, sap or leaves results in painful blisters.

What is the least toxic fish to eat? ›

The Dietary Guidelines for Americans states that to consume those higher amounts, children should only be fed fish from the “Best Choices” list that are even lower in mercury – these fish are anchovies, Atlantic mackerel, catfish, clams, crab, crawfish, flounder, haddock, mullet, oysters, plaice, pollock, salmon, ...

Do dolphins overdose on pufferfish? ›

Pufferfish only release this neurotoxin when attacked. They are poisonous and there is a history of human poisoning. However, for dolphins, it's much more like a narcotic effect. When they take it in small doses, they get high, but they don't die.

Can you eat puffer fish in Florida? ›

Puffer fish caught in Florida waters have been found to contain a naturally occurring toxic substances, Saxitoxin (STX), which can cause serious illness if eaten.

Why are there dead puffer fish on the beach? ›

Deadly 'tasty treats'

"If puffer fish are pulled up by anglers they tend to be dropped on the wharf or in the boat, or just discarded," he said. They are also often seen washed ashore on beaches around the country, where many coastal residents walk their dogs.

Why do people still eat fugu? ›

Thrill-seeking is not the only reason that Japanese pufferfish remains so popular - aside from its distinct, subtle flavor and unique chewy texture, fugu is also low in fat and high in protein. Both fugu skin and meat are used in Japanese cuisine, and the meat is very versatile.

What does blowfish taste like? ›

White-fleshed and high in protein, the fish's meat is said to have a nuanced flavor, full of umami and even a bit of sweetness.

Can you eat puffer fish raw? ›

Pufferfish are considered a delicacy in Japan, often eaten raw as sashimi or cooked in soups. But if the fish are not carefully prepared they can be deadly.

Why can't you touch a puffer fish? ›

The pufferfish's skin is covered in spines and spikes, which are exceedingly hazardous. Carry a toxin called tetrodotoxin (TTX), which is deadly to other fish and humans. You should avoid touching a pufferfish, especially if it is "puffed out." Your hands could be damaged and you could die.

Do pufferfish hurt to touch? ›

These fish are very dangerous to touch because they secrete lethal toxins from their bodies. However, despite their toxic nature, the pufferfish remains a famous and luxurious delicacy for humans in some regions.

Why is my puffer fish swimming against the glass? ›

Fish exhibit many behaviors that tell us how they are feeling, and glass surfing (also known as pacing) is one of them. This is when fish constantly swim up and down the sides of the aquarium glass. One reason they do this is stress. It could mean they aren't happy in their environment, for one reason or another.

Is a dead puffer fish still poisonous? ›

Pufferfish, either alive or dead, can be fatal to both humans and dogs alike if ingested in large enough quantities. The fish doesn't just have to be eaten, even just chewing or licking can lead to a serious case of poisoning.

What happens if you poke a hole in a puffer fish? ›

Of course, this would harm the puffer fish, and if it were unable to heal itself or otherwise recover from the puncture, especially if it was a large wound, the fish would likely die in the wild due to screwed up buoyancy, lack of its defence mechanism (inflation), as well as blood loss and intense pain.

Can pufferfish pop like a balloon? ›

Pufferfish can balloon into a spikey sphere within moments of sensing a nearby threat, and while it may seem like these creatures hold their breath as they inflate, they can actually breathe as they puff up.

Why is my puffer floating at the top of the tank? ›

What does it mean when your fish swim to the top? Usually, your fish go to the surface when they're not getting enough oxygen. Unlike you, they use their gills to breathe the air that's already in the water. However, in some circ*mstances, there's not enough oxygen in the tank for all the fish to breathe easily.

How do you unhook a pufferfish? ›

Cut the skin around the head, slide your fingers under the skin and pull to the tail in one fast motion. Cut the loose skin and remove the head. Now you are ready to cook your blowfish.

Can a puffer fish puff out of water? ›

One idea scientists have about the pufferfish is its puffiness is a defense against predators, Dowd explained. If puffer fish are swimming, they gulp water into a special sack near their belly. But if they are frightened while in the air, perhaps while being fished out of the water, they will also gulp in air.

What happens if a dog eats a puffer fish? ›

They contain a highly potent neurotoxin known as tetrodotoxin in their organs and skin. Pufferfish ingestion can be life-threatening and result in a rapid onset of paralysis which typically begins in the back legs and progresses forward to the respiratory muscles.

Is tetrodotoxin reversible? ›

- Tetrodotoxin (TTX) binds specifically to sodium channels by mimicking the hydrated Na+ ion, denying entry to Na+ ions. It is considered as an irreversible inhibitor.

What is the most powerful neurotoxin in the world? ›

Pål Stenmark regards botulinum toxin – the world's most dangerous poison – as a set of building blocks he can redesign and give new functions.

How much stronger is tetrodotoxin than cyanide? ›

TTX, one of the most powerful neurotoxins known, it is about 1200 times more toxic to humans than cyanide and it has no known antidote.

How common is puffer fish poisoning? ›

The incidence of tetrodotoxin poisoning is very rare but is higher in countries where people eat pufferfish regularly, such as Japan, Taiwan, and some Southeast Asian countries.

How potent is puffer fish poison? ›

Almost all pufferfish contain tetrodotoxin, a substance that makes them foul tasting and often lethal to fish. To humans, tetrodotoxin is deadly, up to 1,200 times more poisonous than cyanide.

How much does tetrodotoxin cost? ›

Frequently bought together
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1mg$201

How bad is puffer fish poison? ›

Almost all puffer fish contain tetrodotoxin, a substance that makes them foul tasting and often lethal. To humans, tetrodotoxin is deadly, up to 1,200 times more poisonous than cyanide. There is enough toxin in one puffer fish to kill 30 adult humans, and there is no known antidote.

How do you remove poison from puffer fish? ›

You can eat the outer skin when cleaned and blanched but there is great skill involved in removing the spines: hold the skin in one hand and slice them all off with a knife in one movement. Remove the eyes. Now gut your fish. Be very precise with your knife because the ovaries and liver contain most of the poison.

How many times can a puffer fish puff before it dies? ›

Is it true that the Pufferfish dies after inflating twice? Puffer fish inflation is a defensive measure, and as such, there is no limit to the number of times an individual can inflate (and deflate).

What is the most poisonous fish? ›

The most venomous known fish is the reef stonefish. It has a remarkable ability to camouflage itself amongst rocks. It is an ambush predator that sits on the bottom waiting for prey to approach. Instead of swimming away if disturbed, it erects 13 venomous spines along its back.

Does fugu taste good? ›

The word f*cku in Japanese literally means “fortune.” Japanese people love fugu. These fish might have poison, but they are delicious and are seen to bring good luck. In Japan, fugu handlers safely process the fish and remove their poison before serving them.

Is cooked blowfish poisonous? ›

Blowfish, known in Japan as fugu, is a highly prized delicacy both as sashimi or as an ingredient in soup, but the fish's liver, ovaries and skin contain the poison tetrodotoxin and the parts must be removed by specially trained and licensed preparers. There is no known antidote to the poison.

Why do people eat blowfish? ›

Thrill-seeking is not the only reason that Japanese pufferfish remains so popular - aside from its distinct, subtle flavor and unique chewy texture, fugu is also low in fat and high in protein. Both fugu skin and meat are used in Japanese cuisine, and the meat is very versatile.

What if my dog sniffed a dead puffer fish? ›

If you suspect your dog has come into contact with a puffer fish, take it to the vet immediately. With urgent treatment your pet will likely recover, but any delay may be fatal.

Is it safe to touch dead pufferfish? ›

No, pufferfish are not poisonous to touch when dead. However, you should refrain from handling them. If you really must handle them, do it with care and wash your hands thoroughly after handling them to avoid any potential contaminants. The toxin (tetrodotoxin) in pufferfish is found mainly in the internal organs.

Does it hurt a puffer fish to puff up? ›

When a puffer fish puffs up, it takes in water to increase its size. This violently forces the puffer's organs to be pressed to the side, inside the body causing the organs to flatten. This creates an extreme amount of stress for the pufferfish. In some cases, the pufferfish dies from this stress.

Which puffer fish are not poisonous? ›

Not all puffers are necessarily poisonous; the flesh of the northern puffer is not toxic (a level of poison can be found in its viscera) and it is considered a delicacy in North America. Takifugu oblongus, for example, is a fugu puffer that is not poisonous, and toxin level varies widely even in fish that are.

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