CDC - Cryptosporidiosis - Diagnosis (2024)

Crypto lives in the intestine of infected humans or animals. An infected person or animal sheds Cryptosporidium parasites in the stool. Millions of Crypto parasites can be released in a bowel movement from an infected human or animal. Shedding begins when the symptoms begin and can last for weeks after the symptoms (e.g., diarrhea) stop. You can become infected after accidentally swallowing the parasite. Crypto may be found in soil, food, water, or surfaces that have been contaminated with the feces from infected humans or animals. Crypto is not spread by contact with blood. Crypto can be spread by:

  • Putting something in your mouth or accidentally swallowing something that has come in contact with the stool of a person or animal infected with Crypto.
  • Swallowing recreational water contaminated with Crypto. Recreational water can be contaminated with sewage or feces from humans or animals.
  • Swallowing water or beverages contaminated by stool from infected humans or animals.
  • Eating uncooked food contaminated with Crypto. All fruits and vegetables you plan to eat raw should be thoroughly washed with uncontaminated water.
  • Touching your mouth with contaminated hands. Hands can become contaminated through a variety of activities, such as:
    • touching surfaces (e.g., toys, bathroom fixtures, changing tables, diaper pails) that have been contaminated by stool from an infected person,
    • changing diapers,
    • caring for an infected person, and
    • handling an infected animal such as a cow or calf.

People with greater exposure to contaminated materials are more at risk for infection 1,2, such as:

  • Children who attend childcare centers, including diaper-aged children
  • Childcare workers
  • Parents of infected children
  • Older adults (ages 75 years and older)
  • People who take care of other people with cryptosporidiosis
  • International travelers
  • Backpackers, hikers, and campers who drink unfiltered, untreated water
  • People who drink from untreated shallow, unprotected wells
  • People, including swimmers, who swallow water from contaminated sources
  • People who handle infected cattle
  • People exposed to human feces through sexual contact

Contaminated water may include water that has not been boiled or filtered, as well as contaminated recreational water sources. Several community-wide outbreaks of cryptosporidiosis have been linked to drinking municipal water or recreational water contaminated with Cryptosporidium.

Cryptosporidium parasites are found in every region of the United States and throughout the world. Travelers to developing countries may be at greater risk for infection because of poorer water treatment and food sanitation, but cryptosporidiosis occurs worldwide. In the United States, an estimated 748,000 cases of cryptosporidiosis occur each year3.

Once infected, people with decreased immunity are most at risk for severe disease. The risk of developing severe disease may differ depending on each person’s degree of immune suppression.

References
  1. Painter JE, Hlavsa MC, Collier SA, Xiao L, Yoder JS. Cryptosporidiosis surveillance — United States, 2011–2012. Morb Mortal Wkly Rep Surveill Summ. 2015;64(3)1–14.
  2. Painter JE, Gargano JW, Yoder JS, Collier SA, Hlavsa MC. Evolving epidemiology of reported cryptosporidiosis cases in the United States, 1995–2012. Epidemiol Infect. 2016;144(8):1792–802.
  3. Scallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson MA, Roy SL, Jones JL, Griffin PM. Foodborne illness acquired in the United States–major pathogens. Emerg Infect Dis. 2011;17(1):7-15.
CDC - Cryptosporidiosis - Diagnosis (2024)

FAQs

What is the gold standard for diagnosis of Cryptosporidium? ›

Direct fluorescent antibody (DFA) assay

This technique offers the highest combination of sensitivity and specificity and is considered the gold standard by many laboratories.

What are the CDC guidelines for Cryptosporidium? ›

To protect themselves, swimmers should avoid ingesting recreational water. To protect others, people infected with cryptosporidiosis should not enter recreational water while ill with diarrhea, and for the first 2 weeks after symptoms have completely resolved, because of prolonged excretion of infectious oocysts.

What is the diagnosis criteria for Cryptosporidium? ›

Diagnosis of cryptosporidiosis is made by examination of stool samples. Because detection of Cryptosporidium can be difficult, patients may be asked to submit several stool samples over several days.

Why is Cryptosporidium hard to detect? ›

People infected with Crypto can shed the parasite irregularly in their poop (for example, one day they shed parasite, the next day they don't, the third day they do) so patients may need to give three samples collected on three different days to help make sure that a negative test result is accurate and really means ...

What is the CT value for Cryptosporidium? ›

When using chlorine, Ct values of at least 7,000 mg · min/liter are required to inactivate 2 log10 units of C. parvum (18).

What is the gold standard investigation for diagnosing? ›

A hypothetical ideal "gold standard" test has a sensitivity of 100% concerning the presence of the disease (it identifies all individuals with a well-defined disease process; it does not have any false-negative results) and a specificity of 100% (it does not falsely identify someone with a condition that does not have ...

Is cryptosporidiosis a reportable disease to the CDC? ›

Cryptosporidiosis is a nationally notifiable disease. This means that healthcare providers and laboratories that diagnose cases of laboratory-confirmed cryptosporidiosis are required to report those cases to their local or state health departments, which in turn report the cases to CDC.

Do I need to see a doctor for Cryptosporidium? ›

If you think you have cryptosporidium or giardia, this is what you should do. Go to your doctor. They may ask to test a specimen (small amount) of your faeces for cryptosporidium or giardia. Your doctor will give you advice on how to collect the specimen and what to do with it.

Does Cryptosporidium ever go away? ›

In healthy people, symptoms usually last about 2 weeks. The symptoms may go in cycles in which you seem to get better for a few days, then feel worse, before the illness ends. Most healthy people do not need any specific treatment and will recover on their own.

What to do if you have Cryptosporidium? ›

The most important treatment is drinking plenty of fluids to keep hydrated. Your provider may prescribe oral or IV hydration or antidiarrheal medications. Antiprotozoal medication can also be used to treat cryptosporidiosis in people with healthy immune systems.

What kills Cryptosporidium? ›

Cryptosporidium is resistant to chlorine disinfection so it is tougher to kill than most disease-causing germs. The usual disinfectants, including most commonly used bleach solutions, have little effect on the parasite. An application of hydrogen peroxide seems to work best.

What is the incubation period of cryptosporidiosis? ›

Infection with Cryptosporidium spp. and genotypes results in a wide range of signs and symptoms. The incubation period is an average of 7 days (range: 2–10 days). Immunocompetent patients may present with diarrheal illness that is self-limiting, typically resolving within 2–3 weeks.

What does Cryptosporidium poop look like? ›

In people with a healthy immune system, the main symptom of cryptosporidiosis is watery, self-limiting diarrhea. Symptoms will normally start between 2 and 10 days after a person acquires the virus. However, the effects of the parasite can last anywhere from a few days to longer than 4 weeks.

Can Cryptosporidium be mild? ›

It is a mild disease in healthy people. It is often more severe in small children and elderly people and can be very serious in those people who are immunocompromised (such as patients undergoing cancer treatment, those living with HIV). If you have cryptosporidiosis, how do you limit spread to other people?

What does giardia poop look like? ›

Key points about giardiasis

Giardiasis is an infection caused by a parasite called Giardia. It causes diarrhea. Symptoms include explosive, watery, greasy, foul-smelling stools, bloating, nausea, pain, gas, fatigue, and loss of appetite.

What is considered the gold standard of diagnosis in infectious diseases? ›

Culture is normally the gold standard for identification of organisms, but results may not be available for days or weeks, and not all pathogens can be cultured, making alternative tests useful. When a pathogen is cultured and identified, the laboratory can also assess its susceptibility to antimicrobial drugs.

What is the gold standard in the diagnosis of bacterial infection? ›

The culture of the bacterial species with antibiotic sensitivity testing is considered the gold standard laboratory test.

What is acid-fast test for Cryptosporidium? ›

Types of tests

Modified acid-fast staining procedure is useful for the identification of oocysts (which may be difficult to detect with routine stains, such as trichrome). Cryptosporidium species stain a pinkish-red color on a uniformly green background.

How do you test for Giardia and Cryptosporidium? ›

Merifluor® C/G Treated Microscope Slides

Direct fluorescent assay for the detection of Cryptosporidium and Giardia. A simple, highly sensitive stain to detect Cryptosporidium and Giardia.

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